Histone H2B Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA141614
Suggested positive control: PBMC.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
|Synthetic peptide corresponding to a portion of human Histone-H2B.|
|PBS with 0.05% BSA and 0.05% sodium azide|
|RP1-193B12.10, H2B/d, H2BFD, HIST1H3I, MGC125414, MGC125415, MGC125416, MGC9388|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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