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Histone H3.3 Rabbit anti-Bovine, Chicken, Drosophila, Equine, Human, Marsupial, Mouse, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523288

Catalog No. PIPA523288


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Description

Description

Histone H3.3 is a nuclear protein and a replication-independent member of the histone H3 family that has a role in nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. H3.3 constitutes the predomit form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. It has a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Expression of H3F3A is common throughout the cell cycle independent of DNA synthesis.
Specifications

Specifications

Histone H3.3
Polyclonal
Unconjugated
H3F3B
Liquid
H3F3A, H3f3b, His3.3A
Synthetic peptide (119 TIMPKDIQLARRIRGERA 136) of Histone H3.3 protein.
Protein A
RUO
Antibody
Polyclonal
Bovine, Chicken, Drosophila, Equine, Human, Marsupial, Mouse, Non-human primate
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
P68432, P84247, P84249, P84243, P84244
Histone H3, H3.3A, H3.3B, H3F3, H3F3A, H3F3B
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
100054462, 15078, 15081, 3020, 3021, 326601, 33736, 396233, 617051
Documents
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