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hydroxymethylbilane synthase, Mouse, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human HMBS protein.

Manufacturer:  Abnova Corporation H00003145B01

Catalog No. 89-005-544


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Description

Description

This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq

Sequence: MSGNGNAAATAEENSPKMRVIRVGTRKSQLARIQTDSVVATLKASYPGLQFEIIAMSTTGDKILDTALSKIGEKSLFTKELEHALEKNEVDLVVHSLKDLPTVLPPGFTIGAICKRENPHDAVVFHPKFVGKTLETLPEKSVVGTSSLRRAAQLQRKFPHLEFRSIRGNLNTRLRKLDEQQEFSAIILATAGLQRMGWHNRVGQILHPEECMYAVGQGALGVEVRAKDQDILDLVGVLHDPETLLRCIAERAFLRHLEGGCSVPVAVHTAMKDGQLYLTGGVWSLDGSDSIQETMQATIHVPAQHEDGPEDDPQLVGITARNIPRGPQLAAQNLGISLANLLLSKGAKNILDVARQLNDAH
Specifications

Specifications

hydroxymethylbilane synthase
Unconjugated
No additive
NM_000190.3
PBG-D|PBGD|UPS
Mouse
50 uL
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Primary
3145
Western Blot
Mouse polyclonal antibody raised against a full-length human HMBS protein.
HMBS
Serum
HMBS
HMBS (NP_000181.2, 1 a.a. ~ 361 a.a) full-length human protein.
RUO
Y
Polyclonal
Human
Documents
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