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hnRNP AB Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527549

Catalog No. PIPA527549


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Description

Description

PA5-27549 targets hnRNP A/B in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-27549 immunogen is recombit fragment corresponding to a region within amino acids 8 and 170 of Human hnRNP A/B. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Specifications

Specifications

hnRNP AB
Polyclonal
Unconjugated
HNRNPAB
Liquid
HNRNPAB
Recombit fragment corresponding to a region within amino acids 8 and 170 of Human hnRNP A/B
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
ChIP assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.26 mg/mL
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Q99729
ABBP1, HNRPAB, ABBP-1, APOBEC1-binding protein 1, apobec-1 binding protein 1, apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1-binding protein 1, hnRNP A/B, hnRNP type A/B protein
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
3182
Documents
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