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HOXA9 Rabbit anti-Canine, Chicken, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523410

Catalog No. PIPA523410


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Description

Description

HOXA9 (Homeobox protein A9) is a protein that in humans is encoded by the HOXA9 gene. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This HOXA9 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. HOXA9 is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Transfection studies showed that HOXA9 is a strong transcriptional repressor; it suppresses the transcription of the luciferase reporter gene driven by a 124-base pair OPN promoter fragment containing both Smad3 and HOX binding sites.
Specifications

Specifications

HOXA9
Polyclonal
Unconjugated
HOXA9
Liquid
HOXA9
Synthetic peptide (199 NWLHARSTRKKRCPYTKH 216) of HOXA9 protein.
Protein A
RUO
Antibody
Polyclonal
Canine, Chicken, Human, Mouse, Non-human primate, Rat
Immunohistochemistry (Paraffin)
1.0 mg/mL
PBS with 0.05% sodium azide
Q98924, P31269, P09631
ABD-B, HOX1, HOX1.7, HOX1G, homeobox protein Hox-1G, homeobox protein Hox-A9, homeodomain protein HOXA9
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
15405, 297099, 3205, 396096, 482372
Documents
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