HOXA9 Rabbit anti-Canine, Chicken, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523410
DescriptionHOXA9 (Homeobox protein A9) is a protein that in humans is encoded by the HOXA9 gene. In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This HOXA9 is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. HOXA9 is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Transfection studies showed that HOXA9 is a strong transcriptional repressor; it suppresses the transcription of the luciferase reporter gene driven by a 124-base pair OPN promoter fragment containing both Smad3 and HOX binding sites.
|Synthetic peptide (199 NWLHARSTRKKRCPYTKH 216) of HOXA9 protein.|
|Canine, Chicken, Human, Mouse, Non-human primate, Rat|
|PBS with 0.05% sodium azide|
|Q98924, P31269, P09631|
|ABD-B, HOX1, HOX1.7, HOX1G, homeobox protein Hox-1G, homeobox protein Hox-A9, homeodomain protein HOXA9|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|15405, 297099, 3205, 396096, 482372|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok