HOXB4 Rabbit anti-Bovine, Feline, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523366
DescriptionHOX homeobox genes play a role both in the early stem cell function as well as in later stages of hematopoietic differentiation. HOXB4, specifically, is a homeotic selector gene implicated in self-renewal of definitive HSCs. Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induced a switch to the definitive HSC phenotype. Activation of WNT signaling in HSCs induced increased expression of HOXB4. Perturbations of HOX gene expression can cause leukemia.
|Synthetic peptide (154 NPNYAGGEPKRSRTAYTR 171) of HOXB4 protein.|
|Antigen affinity chromatography|
|Bovine, Feline, Human, Mouse, Non-human primate, Rat|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.05% BSA and 0.05% sodium azide|
|Q08DG5, P17483, P10284|
|HOX-2.6, HOX2, HOX2F, homeo box 2F, homeo box B4, homeobox protein Hox-2.6, homeobox protein Hox-2F, homeobox protein Hox-B4|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|101096120, 15412, 3214, 497988, 768240|
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