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HOXB4 Rabbit anti-Bovine, Feline, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523366

Catalog No. PIPA523366


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Description

Description

HOX homeobox genes play a role both in the early stem cell function as well as in later stages of hematopoietic differentiation. HOXB4, specifically, is a homeotic selector gene implicated in self-renewal of definitive HSCs. Expression of HOXB4 in primitive progenitors combined with culture on hematopoietic stroma induced a switch to the definitive HSC phenotype. Activation of WNT signaling in HSCs induced increased expression of HOXB4. Perturbations of HOX gene expression can cause leukemia.
Specifications

Specifications

HOXB4
Polyclonal
Unconjugated
HOXB4
Liquid
HOXB4
Synthetic peptide (154 NPNYAGGEPKRSRTAYTR 171) of HOXB4 protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Bovine, Feline, Human, Mouse, Non-human primate, Rat
Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q08DG5, P17483, P10284
HOX-2.6, HOX2, HOX2F, homeo box 2F, homeo box B4, homeobox protein Hox-2.6, homeobox protein Hox-2F, homeobox protein Hox-B4
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
101096120, 15412, 3214, 497988, 768240
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