HRI Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA515396

Catalog No. PIPA515396

Description

The HRI gene is localized to 7p22 where its 3′ end slightly overlaps the 3′ end of the gene JTV1. The two genes are transcribed from opposite strands. Studies in rat and rabbit suggest that the HRI gene product phosphorylates the alpha subunit of eukaryotic initiation factor 2. Its kinase activity is induced by low levels of heme and inhibited by the presence of heme.

Specifications

• Antigen: HRI
• Classification: Polyclonal
• Gene: EIF2AK1
• Gene Alias: Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase; Hemin-sensitive initiation factor 2-alpha kinase; Heme-regulated inhibitor; Heme-controlled repressor; HCR; HRI, KIAA1369
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 27102
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Conjugate: Unconjugated
• Gene Accession No.: Q9BQI3
• Gene Symbols: EIF2AK1
• Immunogen: KLH conjugated synthetic peptide between 267-296 amino acids from the central region of human HRI (EIF2AK1)
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG