HSF1 Rat anti-Mouse, Clone: 744509, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA524354
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.Heat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen at both the mRNA and protein level. HSF1 is normally found as a monomer whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. Both HSF1 and HSF2 are known to be induced by proteasome inhibitors of the ubiquitin pathway.
|PBS with 5% trehalose and No Preservative|
|Heat shock factor 1, Heat shock factor protein 1, Heat shock transcription factor 1, HSF 1, hsf1, HSF1, HSTF 1, HSTF1|
|-20° C, Avoid Freeze/Thaw Cycles|
|E. coli-derived recombit mouse HSF1 Thr124-Tyr247|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok