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CD4 Mouse anti-Human, Brilliant Violet 605, Clone: RPA-T4, BD

Mouse Monoclonal Antibody

$195.00 - $395.00

Specifications

Antigen CD4
Isotype IgG1, κ
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Conjugate Brilliant Violet 605
Primary or Secondary Primary
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB562659
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BD Biosciences
562659
25 Tests Each for $195.00
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BDB562658
View Documents
BD Biosciences
562658
100 Tests Each for $395.00
Add to cart
 
Description

Description

The RPA-T4 monoclonal antibody specifically binds to CD4, a 59 kDa single-chain transmembrane glycoprotein that is expressed on T-helper/inducer cell populations. CD4 is also expressed on thymocytes subsets and at lower levels on monocytes and macrophages. CD4 functions as a co-receptor in MHC class II-restricted antigen-induced T cell activation and as a receptor for human immunodeficiency viruses (HIV). This antibody binds to the D1 domain (CDR1 and CDR3 epitopes) of the CD4 antigen and reacts with approximately 80% of thymocytes and 45% of peripheral blood lymphocytes. RPA-T4 is capable of blocking HIV-1, gp120, and inhibits syncytium formation.

This antibody is conjugated to BD Horizon BV605 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 407-nm and Em Max of 602-nm, BD Horizon BV605 can be excited by a violet laser and detected with a standard 610/20-nm filter set. BD Horizon BV605 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an Em max at 605-nm. Due to the excitation of the acceptor dye by the green (532 nm) and yellow-green (561 nm) lasers, there will be significant spillover into the PE and BD Horizon PE-CF594 detectors off the green or yellow-green lasers. BD Horizon BV605 conjugates are very bright, often exhibiting brightness equivalent to PE conjugates and can be used as a third color off of the violet laser.

Specifications

Specifications

CD4
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Primary
Murine
Affinity Purified
Monoclonal
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
IgG1, κ
Brilliant Violet 605
Flow Cytometry
RUO
RPA-T4
L3T4; T-cell surface antigen T4/Leu-3; W3/25; CD4 antigen (p55)

For Research Use Only.

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