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Growth Hormone Mouse anti-Human, Clone: 3E2, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MIH9901

Catalog No. PIMIH9901


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Description

Description

MIH9901 targets Human Growth Hormone in ELISA, immunoprecipitation, and radioimmunoassay applications and shows reactivity with Human samples. The MIH9901 immunogen is human Growth Hormone. MIH9901 detects Human Growth Hormone which has a predicted molecular weight of approximately 24 kDa. MIH9901 was formerly sold as a Seradyn product.

Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa. HGH is produced by the somatotroph cells in the pituitary. It acts through binding to membrane receptors that belong to the cytokine receptor subfamily. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature.
Specifications

Specifications

Growth Hormone
Monoclonal
6.71 mg/mL
PBS with 0.09% sodium azide; pH 7.4
P01241
pituitary growth hormone, somatotropin
Mouse
IgG1
1 mg
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Primary
2688
ELISA, Immunoprecipitation, Radioimmune Assays
3E2
Unconjugated
GH1
Liquid
GH1
Human Growth Hormone
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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