HYAL2 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA524223
DescriptionThis gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluro, one of the major glycosaminoglycans of the extracellular matrix. Hyaluro and fragments of hyaluro are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5 ft. UTR.
|PBS with 0.09% sodium azide|
|LUCA2, PH-20 homolog, PH20 homolog, hyal-2, hyaluronidase 2, hyaluronidase-2, hyaluronoglucosaminidase-2, lung carcinoma protein 2, lysosomal hyaluronidase|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|KLH conjugated synthetic peptide between 385-412 amino acids from the C-terminal region of human HYAL2|
|Antigen Affinity Chromatography, Protein A|
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