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HYAL2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA524223

Catalog No. PIPA524223


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Description

Description

This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluro, one of the major glycosaminoglycans of the extracellular matrix. Hyaluro and fragments of hyaluro are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5 ft. UTR.
Specifications

Specifications

HYAL2
Polyclonal
PBS with 0.09% sodium azide
Q12891
LUCA2, PH-20 homolog, PH20 homolog, hyal-2, hyaluronidase 2, hyaluronidase-2, hyaluronoglucosaminidase-2, lung carcinoma protein 2, lysosomal hyaluronidase
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
8692
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
HYAL2
Liquid
HYAL2
KLH conjugated synthetic peptide between 385-412 amino acids from the C-terminal region of human HYAL2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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