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IκBα Mouse anti-Human, Unlabeled, Clone: 25, BD

Mouse Monoclonal Antibody

$213.00 - $427.00

Specifications

Antigen IκBα
Isotype IgG1
Immunogen Human IκBα aa. 145-302
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB610691
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BD Biosciences
610691
150μg
Each for $427.00
Add to cart
 
BDB610690
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BD Biosciences
610690
50μg
Each for $213.00
Add to cart
 
Description

Description

NF-κB is a transcription factor that regulates many cytokine and Ig genes involved in immune response, inflammation, and viral infections. NF-κB is induced by cytokines and lipopolysaccharide (LPS), but is inhibited by glucocorticoids. IκBα/MAD-3 inhibits the DNA-binding activity of NF-κB and related transcription factors. In THP-1 monocytic-like cells, LPS induces the phosphorylation and inactivation of IκBα, which results in the activation of NF-κB. Therefore, phosphorylation of IκBα may induce the dissociation of the IκBα/NF-κB complex.

Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting

Specifications

Specifications

IκBα
Human IκBα aa. 145-302
Unconjugated
Cell Biology
Mouse
Affinity Purified
Monoclonal
MAD-3; I-kappa-B-alpha; IkB-alpha; NFKBIA; NF-kappa-B inhibitor alpha
IgG1
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Western Blot
RUO
25
250μg/mL
Store undiluted at -20°C.
SDS
Product Certifications

For Research Use Only.

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