Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

anti-I-kappa-B-alpha Clone: 6H7L22, Invitrogen™

I-kappa-B-alpha Monoclonal antibody 701098 from Thermo Scientific™ Pierce™ specifically detects I-kappa-B-alpha in Human samples, and it is validated for WB

Manufacturer:  Invitrogen 701098

Encompass

Catalog No. 70-109-8


Add to cart

Description

Description

I kappa B-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity. The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol. The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus. A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha. These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses. In humans, the gene is located on the q arm of chromosome 14.

701098 detects I-kappa-B-alpha in Human samples. 701098 has been successfully used in WB procedures. The immunogen for 701098 is recombinant protein corresponding to amino acids 1-110 of human NF-kappa-B inhibitor alpha.

Applications:

Western Blotting

Specifications

Specifications

I-kappa-B-alpha
Unconjugated
P25963
Rabbit
IgG
Store at 2 to 8°C for up to 1 month. For long term storage, store at -20°C.
Monoclonal
Human
6H7L22
100μg of Protein A antibody in PBS with 0.09% sodium azide;
Purified
Recombinant protein corresponding to amino acids 1-110 of human NF-kappa-B inhibitor alpha
Protein A
Primary
4792
SDS
Documents
Product Certifications
Promotions

Promotions

Provide Content Correction

The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit