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CD275 (B7-H2) Mouse anti-Human, Clone: 136726, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523866

Catalog No. PIMA523866


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Description

Description

In direct ELISAs and Western blots, no cross-reactivity with recombit human (rh) B7-1, rhB7-2, rhB7-H1, rhB7-H3, or recombit mouse B7-H2 is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

Inducible co-stimulator ligand (ICOSL) is a specific ligand on antigen-presenting cells and cells of the peripheral tissue that binds to the inducible co-stimulator receptor (ICOS). ICOS belongs to the CD28/CD152 receptor family that regulates T-cell activation and function. ICOSL is expressed on monocytes, dendritic cells and B cells and can be induced by inflammatory stimuli in peripheral tissue. Binding to ICOSL delivers a co-stimulatory signal for T cell proliferation and cytokine secretion.
Specifications

Specifications

CD275 (B7-H2)
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
O75144
B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653, LICOS, ICOS Ligand
Mouse
IgG2B
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
23308
Flow Cytometry, Neutralization
136726
Unconjugated
ICOSLG
Lyophilized
ICOSLG
Mouse myeloma cell line NS0-derived recombit human B7-H2 Asp19-Ser258
Protein A/G
RUO
Antibody
Monoclonal
Human
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