CTLA-4 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523967
DescriptionCTLA4 is a member of the immunoglobulin superfamilyand encodes a protein which transmits an inhibitory signal to Tcells. The protein contains a V domain, a transmembrane domain, anda cytoplasmic tail. Alternate transcriptional splice variants,encoding different isoforms, have been characterized. Themembrane-bound isoform functions as a homodimer interconnected by adisulfide bond, while the soluble isoform functions as a monomer.Mutations in this gene have been associated with insulin-dependentdiabetes mellitus, Graves disease, Hashimoto thyroiditis, celiacdisease, systemic lupus erythematosus, thyroid-associatedorbitopathy, and other autoimmune diseases.
|KLH conjugated synthetic peptide between 50-78 amino acids from the N-terminal region of human IDDM12|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.09% sodium azide|
|CELIAC3, CTLA-4, GRD4, GSE, ICOS, IDDM12, CD152 isoform, celiac disease 3, cytotoxic T lymphocyte associated antigen 4 short spliced form, cytotoxic T-lymphocyte antigen 4|
|-20° C, Avoid Freeze/Thaw Cycles|
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