IFN-gamma Mouse anti-Human, Alexa Fluor 647, Clone: 4S.B3, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 563495

Catalog No. BDB563495

Description

The 4S.B3 monoclonal antibody specifically binds to interferon-γ(IFN-γ). The immunogen used to generate this hybridoma was partially purified human IFN-γobtained from supernatants of human PBMC stimulated with Staphylococcus aureus. Interferon-γ(IFN-γ) is a potent multifunctional cytokine that is produced by several activated cell types including NK, NKT, CD4+TCRαβ+, CD8+TCRαβ+, and TCRγδ+ T cells. IFN-γexerts its biological effects through specific binding to the high-affinity IFN-γReceptor Complex comprised of IFN-γRα (CD119) and ese influences can involve IFN-γ’s capacity to boost MHC class I and II expression by antigen-presenting cells as well as to direct effects on B cells and T cells themselves. Human IFN-γis a 14-18 kDa glycoprotein containing 143 amino acid residues.

Specifications

• Antigen: IFN-gamma
• Classification: Monoclonal
• Conjugate: Alexa Fluor 647
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: Partially purified human IFN-gamma from supernatants of human PBMC stimulated with Staphylococcus aureus
• Quantity: 50 Tests
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: 4S.B3
• Description: IFNG; Interferon-gamma; IFG; IFI; Type II interferon
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
• Isotype: IgG1 κ