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IFNAR1 Mouse anti-Human, PE, Clone: 85228, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523630

Catalog No. PIMA523630


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Description

Description

In direct ELISAs, does not cross-react with Recombinant human (rh) IFN- gamma R1, rhIFN-gamma R2, Recombinant mouse IFN-alpha / beta R2, rhIL-10 R beta, rhIL-10 R alpha, or rhIL-20 R beta.

Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system (Biron,2001, Kirkwood, 2002). These cytokines produce their effects by binding to the Type 1 Interferon-& Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1 (Kumar et al., 2003).
Specifications

Specifications

IFNAR1
Monoclonal
PE
IFNAR1
Liquid
IFNAR1
Sf 21-derived recombit human IFN-alpha/beta R1 Lys28-Lys436
Protein A/G
RUO
Antibody
Monoclonal
Human
Flow Cytometry
85228
Buffered saline solution with BSA and 0.09% sodium azide
P17181
AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC, CRF2-1, IFN-R-1, IFN-alpha/beta receptor 1, alpha-type antiviral protein, beta-type antiviral protein, cytokine receptor class-II member 1, cytokine receptor family 2 member 1, interferon alpha/beta receptor 1, interferon-alpha/beta receptor alpha chain, interferon-beta receptor 1, type I interferon receptor 1
Mouse
IgG1
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
3454
Documents
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