IFNAR1 Mouse anti-Human, PE, Clone: 85228, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA523630
In direct ELISAs, does not cross-react with Recombinant human (rh) IFN- gamma R1, rhIFN-gamma R2, Recombinant mouse IFN-alpha / beta R2, rhIL-10 R beta, rhIL-10 R alpha, or rhIL-20 R beta.Interferons are widely used therapeutic agents because of their anti tumor and antiviral effects and because of their modulatory effects on the immune system (Biron,2001, Kirkwood, 2002). These cytokines produce their effects by binding to the Type 1 Interferon-& Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is thought to be influenced by phosphorylation of Serine 535 and 539 in the IFNAR1 (Kumar et al., 2003).
|Sf 21-derived recombit human IFN-alpha/beta R1 Lys28-Lys436|
|Buffered saline solution with BSA and 0.09% sodium azide|
|AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC, CRF2-1, IFN-R-1, IFN-alpha/beta receptor 1, alpha-type antiviral protein, beta-type antiviral protein, cytokine receptor class-II member 1, cytokine receptor family 2 member 1, interferon alpha/beta receptor 1, interferon-alpha/beta receptor alpha chain, interferon-beta receptor 1, type I interferon receptor 1|
|4° C, store in dark, DO NOT FREEZE!|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok