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IFN beta Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520390

Catalog No. PIPA520390


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Description

Description

A suggested positive control is A-20 cell lysate. PA5-20390 can be used with blocking peptide PEP-0507.

Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.
Specifications

Specifications

IFN beta
Polyclonal
Unconjugated
IFNB1
Liquid
IFNB1
A 17 amino acid peptide from near the center of human IFN-b.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P01574, P01575
RP11-113D19.1, IFB, IFF, IFNB; IFN-beta; fibroblast interferon; interferon beta
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
15977, 3456
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