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IkB zeta Rabbit anti-Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141088

Catalog No. 01-676-679


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Description

Description

Suggested positive control: Raw cell lysate.

I-kappa-B-zeta (also known as MAIL and INAP) is an ankyrin-repeat-containing nuclear protein that is highly homologous to the IkappaB family member Bcl-3. Transcription of IkappaBzeta is upregulated by stimulation with TLR ligands, IL-1 and IL-6 in cultured B-lymphocytes and monocytes/macrophages, but only faintly so in T-lymphocytes, fibroblasts, and endothelial cells. IkappaB-zeta preferentially associates with the NF-kappaB subunit p50 rather than p65 and recombit IkappaB-zeta proteins inhibit the DNA binding of the p65/p50 heterodimer and the p50/p50 homodimer.
Specifications

Specifications

IkB zeta
Polyclonal
Unconjugated
Nfkbiz
Liquid
NFKBIZ
Synthetic peptides corresponding to residues 186-199 and 585-600 of mouse IkBz protein.
Protein G
RUO
Antibody
Polyclonal
Mouse
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q9EST8
FLJ30225, FLJ34463, IKBZ, INAP, MAIL
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
80859
Documents
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