IKZF3 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA525564
This antibody is predicted to react with bovine based on sequence homology.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described.
|KLH conjugated synthetic peptide between 76-103 amino acids from the central region of human IKZF3|
|Protein A, Antigen Affinity Chromatography|
|PBS with 0.09% sodium azide|
|AIO, AIOLOS, ZNFN1A3, ikaros family zinc finger protein 3, zinc finger protein Aiolos, zinc finger protein, subfamily 1A, 3 (Aiolos)|
|-20° C, Avoid Freeze/Thaw Cycles|
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