Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CD122 Mouse anti-Human, Clone: 27302, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523816

Catalog No. PIMA523816


Add to cart

Description

Description

In direct ELISAs, no cross-reactivity with recombit human (rh) IL-2 R alpha, rh gamma c, rhIL-4 R, or rhIL-6 R is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and is present in 3 forms. The low affinity form of CD122 is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from CD122. The protein encoded by the CD122 gene represents the beta subunit and is a type I membrane protein. Diseases associate with CD122 protein dysfunction include oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.
Specifications

Specifications

CD122
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P14784
CD122, IL15RB, P70-75, CD122 antigen, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, high affinity IL-2 receptor beta subunit, high affinity IL-2 receptor subunit beta, interleukin 15 receptor, beta, interleukin-2 receptor subunit beta, p75
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
3560
Flow Cytometry, Immunohistochemistry, Neutralization
27302
Unconjugated
IL2RB
Lyophilized
IL2RB
Sf 21-derived recombit human IL-2 R beta Ala27-Asp239
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit