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IL1R2 Mouse anti-Human, Clone: 34141, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523820

Catalog No. PIMA523820


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Description

Description

When used in combination with the biotinylated human IL-1 RII affinity purified polyclonal detection antibody in sandwich ELISAs, no significant cross-reactivity or interference was observed with recombit human (rh) IL-1ra, rhIL-1 RI, recombit mouse IL-1ra, or recombit rat IL-1ra. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.

The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Two alternatively spliced transcript variants encoding the same protein have been reported.
Specifications

Specifications

IL1R2
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P27930
CD121b, IL1RB, CD121 antigen-like family member B, CDw121b, IL-1 type II receptor, IL-1R-2, IL-1R-beta, IL-1RT-2, IL-1RT2, antigen CDw121b, interleukin-1 receptor beta, interleukin-1 receptor type 2, interleukin-1 receptor type II, type II interleukin-1 receptor, beta, ILR2
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
7850
ELISA, Neutralization, Western Blot
34141
Unconjugated
IL1R2
Lyophilized
IL1R2
Sf 21-derived recombit human IL-1 RII Phe14-Glu343 (Ser56Gly and Glu297Gly)
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
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