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IL-12 p35 Sheep anti-Human, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen PA175190

Catalog No. PIPA175190


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Description

Description

PA1-75190 specifically detects IL-12A p35 subunit. PA1-75190 has been successfully used in ELISA applications. The PA1-75190 immunogen is Recombit IL-12A.

This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.
Specifications

Specifications

IL-12 p35
Polyclonal
PBS with 0.09% sodium azide
P29459
CLMF, IL-12A, NFSK, NKSF1, P35, IL12p35
Sheep
IgG
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
3592
ELISA
Unconjugated
IL12A
Liquid
IL12A
Recombit human IL-12A
Affinity chromatography
RUO
Antibody
Polyclonal
Human
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