IL-13 Sheep anti-Human, Polyclonal, Invitrogen™
Sheep Polyclonal Antibody
Supplier: Thermo Scientific PA175196
PA1-75196 specifically detects IL-13. PA1-75196 has been successfully used in ELISA applications. The PA1-75196 immunogen is Recombit IL-13.IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
|ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600
|-20° C, Avoid Freeze/Thaw Cycles
|Recombit human IL-13
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