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IL-13 Sheep anti-Human, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Supplier:  Thermo Scientific PA175196

Catalog No. PIPA175196

Item Discontinued This item has been discontinued by the supplier and is no longer available. Please reach out to your sales representative.


Description

Description

PA1-75196 specifically detects IL-13. PA1-75196 has been successfully used in ELISA applications. The PA1-75196 immunogen is Recombit IL-13.

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and is involved in regulating inflammatory and immune responses. IL-13 down-regulates macrophage activity, thereby inhibiting the production of pro-inflammatory cytokines and chemokines, and is involved in allergen-induced asthma through mechanisms independent of IgE and eosinophils. IL-13 also regulates several stages of B cell maturation and differentiation, up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. Structurally, IL-13 closely resembles IL-3, IL-4, IL-5 and GM-CSF. The gene encoding IL-13, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with the IL-13 gene particularly close to IL4.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

IL-13
Polyclonal
IL13
ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600
Sheep
Affinity chromatography
RUO
3596
-20° C, Avoid Freeze/Thaw Cycles
Liquid
ELISA
Unconjugated
P35225
IL13
Recombit human IL-13
500 μg
Primary
Human
Antibody
IgG
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