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IL-17A Rat anti-Mouse, Brilliant Violet 510, Clone: TC11-18H10, BD

Rat Monoclonal Antibody

Manufacturer:  BD Biosciences 564168

Catalog No. BDB564168


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Description

Description

The TC11-18H10 monoclonal antibody specifically binds to recombinant and natural mouse IL-17A proteins. IL-17A, also known as CTLA-8, is a T cell-derived cytokine that promotes inflammatory responses. Mouse IL-17A is a proinflammatory cytokine that can induce the release of IL-6 by mouse stromal cells. It has been shown to support the growth of hemopoietic progenitors in vitro; it can also stimulate granulopoiesis in vivo. The TC11-18H10 antibody has been reported to neutralize IL-17A activity. Recent studies have shown that IL-17A is produced by a unique subset of Th17 cells that develop along a pathway distinct from the Th1- and Th2- cell differentiation pathways. The mouse IL-17A cDNA was isolated from a cDNA library generated from TCR αβ +CD4-CD8- thymocytes.

Specifications

Specifications

IL-17A
TC11-18H10
Brilliant Violet 510
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Rat
IgG1, κ
RUO
Primary
Murine
Flow Cytometry
0.2mg/mL
Interleukin-17A; Il17a; Cytotoxic T-lymphocyte-associated antigen; CTLA-8
Affinity Purified
Recombinant Mouse IL-17A Protein
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Documents
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