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MilliporeSigma™ anti-IL-2 APC, Clone: JES6-5H4,

Rat Monoclonal Antibody

$153.70 - $343.00

Specifications

Antigen IL-2
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Format Purified
Formulation Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
MABF1505MI
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MilliporeSigma™
MABF1505
25μg
Each for $153.70
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MABF1506MI
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MilliporeSigma™
MABF1506
100μg
Each for $343.00
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Description

Description

Specifically detects IL-2 Clone: JES6-5H4 in Mouse samples, and it is validated for Flow Cytometry

The JES6-5H4 antibody binds to mouse Interleukin-2 (IL-2), a 17kDa cytokine that is secreted by activated T cells. This cytokine acts as an autocrine stimulatory factor for T cell proliferation, differentiation and survival, as well as being an effective activator of B cells and inducer of NK cell cytotoxic functions. IL-2 plays a key modulatory role in the differentiation of T cells toward either Th17 or T regulatory (Treg) cell types and is important for Treg cell function. The IL-2 receptor (IL-2R) is a complex consisting of an IL-2R alpha chain (CD25), along with the IL-2R beta chain (CD122) and the common gamma chain (CD132). IL-2 may also bind with low affinity to the T cell surface protein CD25 alone, although this interaction does not induce cell signaling.
Specifications

Specifications

IL-2
Monoclonal
Purified Rat monoclonal containing 10mM NaH2PO4, 150mM NaCl, 0.09% NaN3, 0.1% gelatin, pH 7.2.
Flow Cytometry
IgG2b, κ
P04351
2°C to 8°C undiluted for one year from date of shipment protected from light; Do not freeze
Inflammation, Immunology
Primary
Purified
JES6-5H4
Rat
Proprietary immunogen
Il2, Il-2
RUO
Purified by size-exclusion chromatography
SDS
Product Certifications

For Research Use Only

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