IL-2 Mouse anti-Human, Clone: 297C 16G2, Invitrogen™  

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen AHC0622

Catalog No. AHC0622

Description

Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.

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Specifications

• Antigen: IL-2
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide; pH 7.4
• Gene Accession No.: P60568
• Gene Alias: T-cell growth factor, TCGF, interleukin-2
• Host Species: Mouse
• Isotype: IgG2b, kappa
• Quantity: 500 μg
• Storage Requirements: 4° C
• Primary or Secondary: Primary
• Gene ID (Entrez): 3558

• Applications: ELISA, Immunohistochemistry
• Clone: 297C 16G2
• Conjugate: Unconjugated
• Gene: IL2
• Format: Liquid
• Gene Symbols: IL2
• Immunogen: Purified recombit human IL-2
• Purification Method: Protein A
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human