IL-2 Rat anti-Mouse, Clone: JES6-IAI2, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA523798
Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.Interleukin 2 (IL-2) is an immuno-modulatory cytokine that is important for the proliferation of activated T cells, differentiation of B cells, natural killer cells, monocytes and macrophages. IL-2 signals through the IL-2 receptor (IL-2R), a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL-4) and interleukin 7 (IL-7). The expression of the IL-2 gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a gene similar to IL-2 in mice leads to an ulcerative colitis-like disease that suggests an essential role of this gene in the immune response to antigenic stimuli.
|PBS with 5% trehalose and No Preservative|
|T-cell growth factor, TCGF, interleukin-2|
|-20° C, Avoid Freeze/Thaw Cycles|
|E. coli-derived recombit mouse IL-2|
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