Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

IL23R Mouse anti-Human, Clone: 218213, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523935

Catalog No. PIMA523935


Add to cart

Description

Description

This antibody does not cross-react with Recombinant mouse (rm) IL-23 R. Reconstitute at 0.5 mg/mL in sterile PBS.

IL-23R is a 629 aa, novel subunit of the receptor for cytokine IL23A/IL23 which pairs with the receptor molecule IL12RB1/IL12R beta 1and thus take part in IL23A signaling. Signal transduction analysis confirms that this protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner. Alternative splicing results in six spliced isoforms of IL-23R. Reports suggest that IL-23R plays an important role in psoriasis pathogenesis and is also a potential therapeutic target in inflammatory bowel disease.
Specifications

Specifications

IL23R
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
Q5VWK5
IBD17, IL-23 receptor, IL-23R, interleukin 23 receptor, interleukin-23 receptor
Mouse
IgG2B
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
149233
Western Blot
218213
Unconjugated
IL23R
Lyophilized
IL23R
Mouse myeloma cell line NS0-derived recombit human IL-23 R Gly24-Ile354
Protein A/G
RUO
Antibody
Monoclonal
Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit