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anti-IL-27 Clone: 7H7L10, Invitrogen™

IL-27 Monoclonal antibody 701073 from Thermo Scientific™ Pierce™ specifically detects IL-27 in Human samples, and it is validated for WB

Manufacturer:  Invitrogen 701073

Encompass

Catalog No. 70-107-3


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Description

Description

Interleukin 27, or IL-27 is a cytokine belonging to the IL-12 family. It is a heterodimeric cytokine composed of EBI3 and p28 subunits. IL-27 is produced by activated dendritic cells and macrophages in response to Toll-like receptor ligands and pro-inflammatory cytokines. IL-27 promotes CD4+ T cell differentiation to the Th1 lineage by inducing expression of the transcription factor T-bet and up regulating IL-12R beta2, which in turn suppresses Th2 and Th17 differentiation and proliferation. In humans, the gene is located on the p arm of chromosome 16.

701073 detects IL-27 in Human samples. 701073 has been successfully used in WB procedures. The immunogen for 701073 is recombinant protein corresponding to amino acids 20-189 of human IL-27.

Applications:

Western Blotting

Specifications

Specifications

IL-27
Unconjugated
Q8NEV9
Rabbit
IgG
Store at 2 to 8°C for up to 1 month. For long term storage, store at -20°C.
Monoclonal
Human
7H7L10
100μg of Protein A antibody in PBS with 0.09% sodium azide;
Purified
Recombinant protein corresponding to amino acids 20-189 of human IL-27
Protein A
Primary
246778
SDS
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