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IL-3 Sheep anti-Human, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen PA175208

Catalog No. PIPA175208


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Description

Description

PA1-75208 specifically detects IL-3. PA1-75208 has been successfully used in ELISA applications. The PA1-75208 immunogen is Recombit IL-3.

Interleukin 3 (IL-3), also called Mast Cell Growth Factor (MCGF), Multi-Colony Stimulating Factor (multi-CSF), or Eosinophil-CSF (E-CSF), is produced by activated T cells, mast cells and eosinophils. IL-3 is a hematopoietic growth factor that stimulates colony formation of erythroid, megakaryocyte, neutrophil, eosinophil, basophil, mast cell and monocytic lineages. Most of these functions are enhanced or dependent on co-stimulation with other cytokines. Human and mouse IL-3 share only 29% sequence identity at the amino acid level. The bioactivity of IL-3 is highly species specific. For example, human IL-3 has no activity on mouse cells. IL-3 is a potent growth promoting cytokine. IL-3 is capable of supporting the proliferation of a broad range of hematopoietic cell types, and is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. IL-3 has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
Specifications

Specifications

IL-3
Polyclonal
PBS with 0.09% sodium azide
P08700
IL-3, MCGF, MGC79398, MGC79399, MULTI-CSF
Sheep
IgG
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
3562
ELISA
Unconjugated
IL3
Liquid
IL3
Recombit human IL-3
Affinity chromatography
RUO
Antibody
Polyclonal
Human
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