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CD123, PerCP, clone: 151231, Invitrogen™

Rat Monoclonal Antibody

Manufacturer:  Invitrogen MA523601

Catalog No. PIMA523601

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. It is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. It is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.

In direct ELISAs and Western blots, no cross-reactivity with recombinant human IL-3 R alpha and recombinant mouse IL-3 R beta is observed.
Specifications

Specifications

CD123
Monoclonal
PerCP
Il3ra
Liquid
IL3RA
Sf-21 derived recombinant mouse IL-3 R alpha/CD123 Ser17-Lys331
Protein A/G
RUO
Antibody
Monoclonal
Murine
Flow Cytometry
151231
Buffered saline solution with BSA and 0.1% sodium azide
P26952
CD123, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra, CD123 antigen, IL-3 receptor alpha SP2 isoform, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, interleukin-3 receptor subunit alpha
Rat
IgG2A
100 Tests
Store at 4°C, store in the dark, do not freeze
Primary
16188
Documents
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