CD123, PerCP, clone: 151231, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA523601
IL-3Ra (Interleukin-3 receptor subunit alpha) belongs to the type I cytokine receptor family and is a heterodimer with a unique alpha chain paired with the common beta (beta c or CDw131) subunit. It is responsible for the transmission of signal of Interleukin-3. IL-3Ra and IL-3Rb chain heterodimerization is induced by Interleukin-3, which is required for receptor activation but not high affinity binding. It is also reported that IL-3Ra subunits are overexpressed on acute myeloid leukemia (AML) blasts compared with normal hematopoietic cells and are thus potential targets for novel therapeutic agents.In direct ELISAs and Western blots, no cross-reactivity with recombinant human IL-3 R alpha and recombinant mouse IL-3 R beta is observed.
|Sf-21 derived recombinant mouse IL-3 R alpha/CD123 Ser17-Lys331|
|Buffered saline solution with BSA and 0.1% sodium azide|
|CD123, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra, CD123 antigen, IL-3 receptor alpha SP2 isoform, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA, interleukin-3 receptor subunit alpha|
|Store at 4°C, store in the dark, do not freeze|
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