IL-32 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523199
DescriptionIL-32 is a 234 amino acid member of the cytokine family which plays an important role in innate and adaptive immune responses. It contains a tyrosine sulfation site, three potential N-myristoylation sites, multiple putative phosphorylation sites and a RGD cell-attachment sequence. IL-32 shows increased expression after activation of T lymphocytes and natural killer cells by IL-2 or mitogens. Human IL-32 exists as four splice variants. Reports suggest that it activates typical cytokine signal pathways of nuclear factor-kappa B (NF-kappaB) and p38 mitogen-activated protein kinase. It induces the production of various cytokines such as TNFA/TNF-alpha, macrophage inflammatory protein (MIP)-2 and IL-8, and has a possible role in inflammatory/autoimmune diseases like chronic obstructive pulmonary disease, Crohn’s disease and psoriasis. It is ubiquitously expressed in most tissues with selective expression in lymphocytes and more prominently in immune cells.
|Synthetic peptide (210 QSYGAPRGDKEELTPQKC 227) of IL-32/Natural killer cells protein 4 protein.|
|PBS with 0.05% BSA and 0.05% sodium azide|
|IL-32alpha, IL-32beta, IL-32delta, IL-32gamma, NK4, TAIF, TAIFa, TAIFb, TAIFc, TAIFd, interleukin-32, interleukin-32 eta, interleukin-32 small, interleukin-32 theta, natural killer cell transcript 4, natural killer cells protein 4, tumor necrosis factor alpha-inducing factor|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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