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IL-4 Mouse anti-Rat, Clone: 56567, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523753

Catalog No. PIMA523753


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Description

Description

This antibody does not cross-react with Recombinant human IL-4 or Recombinant mouse IL-4. Reconstitute at 0.5 mg/mL in sterile PBS.

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
Specifications

Specifications

IL-4
Monoclonal
0.5 mg/mL
PBS with 5% trehalose and No Preservative
P20096
B cell growth factor 1, BSF-1, B_cell stimulatory factor 1, binetrakin, interleukin-4, lymphocyte stimulatory factor 1, pitrakinra
Mouse
IgG2b
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
287287
ELISA, Western Blot
56567
Unconjugated
Il4
Lyophilized
IL4
E. coli-derived recombit rat IL-4 Cys25-Ser147
Protein A/G
RUO
Antibody
Monoclonal
Rat
Documents
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