IL-5 Rat anti-Human, Clone: TRFK5, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen MA523690
In sandwich ELISAs, no cross-reactivity with recombit human (rh) IL-3, rhGM-CSF, recombit mouse (rm) IL-5, rhIL-5, rmIL-3, or rmGM-CSF is observed. Reconstitute at 0.5 mg/mL in sterile PBS. Endoxin level is <0.10 EU per 1 µg of the antibody by the LAL method.IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
|PBS with 5% trehalose and No Preservative|
|B cell differentiation factor I, B-cell differentiation factor I, T-cell replacing factor, eosinophil differentiation factor, interleukin-5|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Flow Cytometry, Neutralization|
|Mouse T cell clone-derived partially purified recombit mouse IL-5|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok