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IL5RA Mouse anti-Human, APC, Clone: 26815, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523581

Catalog No. PIMA523581


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Description

Description

In direct ELISAs and Western blots, this antibody does not cross-react with recombit human (rh) IL-5 R beta, rhIL-9 R, rhIL-4 R, rmIL-5 R alpha, or rhIL-13 R alpha 1.

The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Six alternatively spliced transcript variants encoding three distinct isoforms have been reported.
Specifications

Specifications

IL5RA
Monoclonal
APC
IL5RA
Liquid
IL5RA
Sf 21-derived recombit human IL-5R alpha/CD125 Asp21-Arg335
Protein A/G
RUO
Antibody
Monoclonal
Human
Flow Cytometry
26815
Buffered saline solution with BSA and 0.09% sodium azide
Q01344
CD125, CDw125, HSIL5R3, IL5R, CD125 antigen, IL-5 receptor subunit alpha, IL-5R subunit alpha, interleukin 5 receptor type 3, interleukin-5 receptor alpha chain, interleukin-5 receptor subunit alpha
Mouse
IgG1
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
3568
Documents
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