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IL-8 (CXCL8) Sheep anti-Human, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Supplier:  Thermo Scientific PA175220

Catalog No. PIPA175220

Item Discontinued This item has been discontinued by the supplier and is no longer available. Please reach out to your sales representative.


Description

Description

PA1-75220 specifically detects IL-8. PA1-75220 has been successfully used in ELISA applications. The PA1-75220 immunogen is Recombit IL-8.

Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3′-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties, including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

IL-8 (CXCL8)
Polyclonal
CXCL8
RP11-537A6.8, ANX7, SNX, SYNEXIN
Sheep
Affinity chromatography
RUO
3576
-20° C, Avoid Freeze/Thaw Cycles
Liquid
ELISA
Unconjugated
P10145
CXCL8
Recombit human IL-8
500 μg
Primary
Human
Antibody
IgG
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