IL-9 Receptor Alpha (CD129) Mouse anti-Human, NA/LE, Unlabeled, Clone: AH9R7, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 563606
The AH9R7 monoclonal antibody specifically binds to the Interleukin-9 Receptor (IL-9R, IL-9R α ) also known as CD129. CD129 is a Type I transmembrane glycoprotein and a Type I Cytokine Receptor (Hemopoietin) Superfamily member. The high-affinity, signaling IL-9 Receptor complex is comprised of CD129 (IL-9 Receptor alpha chain subunit) and CD132 (common γchain/ γc). CD129 is expressed by hematopoietic progenitors, thymocytes, T cells, B cells, macrophages, eosinophils, mast cells, epithelia cells, muscle cells and neurons. IL-9 signals through the IL-9R complex (ie, through JAK, STAT and related signal pathways) to regulate the growth, proliferation, differentiation and survival of myeloid and erythroid progenitor cells, thymocytes, T cells, B cells and some tumor cells.
|IL-9 Receptor Alpha (CD129)|
|CD129; Interleukin-9 receptor; IL-9R alpha chain; IL-9Rα|
|Human IL9R Transfected Cell Line|
|Store undiluted at 4°C|
|No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered. Endotoxin level is ≤0.01 EU/μg (≤0.001 ng/μg) of protein as determined by the LAL assay.|
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