IL10RA Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527772
PA5-27772 targets IL10 Receptor alpha in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-27772 immunogen is recombit fragment corresponding to a region within amino acids 216 and 518 of Human IL10 Receptor alpha. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.
|Recombit fragment corresponding to a region within amino acids 216 and 518 of Human IL10 Receptor alpha|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|CD210a, CDW210A, HIL-10R, IL-10R1, IL10R, IL-10 receptor subunit alpha, IL-10R subunit 1, IL-10R subunit alpha, IL-10RA, interleukin-10 receptor alpha chain, interleukin-10 receptor subunit 1, interleukin-10 receptor subunit alpha|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok