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IL-12 p35 Mouse anti-Human, Mouse, PE, Clone: 27537, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA523559

Catalog No. PIMA523559


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Description

Description

This antibody detects the p35 subunit either as part of a p40/p35 heterodimer or as a free subunit after reduction of the heterodimer. This antibody does not recognize IL-12 p40 homodimers but shows strong cross-reactivity with the p35 subunits from porcine and mouse systems.

IL-35, or Interleukin 35 is a cytokine belonging to the IL12 family, that is produced by regulatory T cells. It is a dimeric protein composed of IL-12-alpha and IL-27-beta chains. Members of this class of cytokines are important in influencing T helper cell differentiation and supressing inflammatory response. IL-35 is known to induce proliferation of regulatory T cells, and reduce the activity of helper Th17 cells.
Specifications

Specifications

IL-12 p35
Monoclonal
PE
IL12A
Liquid
IL12A
Sf 21-derived recombit human IL-12/IL-35 p35 Arg23-Ser219
Protein A/G
RUO
Antibody
Monoclonal
Human, Mouse
Flow Cytometry
27537
Buffered saline solution with BSA and 0.09% sodium azide
P29459, P43431
CLMF, IL-12A, NFSK, NKSF1, P35, CLMF p35, IL-12 subunit p35, IL-12, subunit p35, IL35 subunit, NF cell stimulatory factor chain 1, NK cell stimulatory factor chain 1, cytotoxic lymphocyte maturation factor 1, p35, cytotoxic lymphocyte maturation factor 35 kDa subunit, interleukin 12, p35, interleukin-12 alpha chain, interleukin-12 subunit alpha, natural killer cell stimulatory factor 1, 35 kD subunit, IL12p35
Mouse
IgG1
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
16159, 3592
Documents
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