IL-4 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA525165
This antibody is predicted to react with non-human primate based on sequence homology.Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
|KLH conjugated synthetic peptide between 122-150 amino acids from the C-terminal region of human L4|
|Antigen Affinity Chromatography, Protein A|
|Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.09% sodium azide|
|BCGF-1, BCGF1, BSF-1, BSF1, IL-4, B cell growth factor 1, B_cell stimulatory factor 1, binetrakin, interleukin-4, lymphocyte stimulatory factor 1, pitrakinra|
|-20° C, Avoid Freeze/Thaw Cycles|
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