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ILK Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527484

Catalog No. PIPA527484


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Description

Description

PA5-27484 targets ILK in WB applications and shows reactivity with Human samples. The PA5-27484 immunogen is recombit fragment corresponding to a region within amino acids 1 and 257 of Human ILK. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. This gene encodes a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Specifications

Specifications

ILK
Polyclonal
Unconjugated
ILK
Liquid
ILK
Recombit fragment corresponding to a region within amino acids 1 and 257 of Human ILK
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunoprecipitation, Western Blot
0.8 mg/mL
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Q13418
ILK-2, P59, 59 kDa serine/threonine-protein kinase, ILK-1, integrin-linked kinase-2, integrin-linked protein kinase, p59ILK
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
3611
Documents
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