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ALS2CR2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520036

Catalog No. PIPA520036


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Description

Description

In Western blot applications, this antibody detects a band at ~34kDa. A suggested positive control is human heart tissue lysate. PA5-20036 can be used with blocking peptide PEP-0155.

ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family. Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1-b converting enzyme of Fas-induced apotosis. This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival, suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.
Specifications

Specifications

ALS2CR2
Polyclonal
Unconjugated
STRADB
Liquid
STRADB
A synthetic peptide corresponding to amino acids at the C-terminus of human ILPIP.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9C0K7
PRO1038, ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK; ILP-interacting protein ILPIPA; STE20-related kinase adapter protein beta; STRAD beta; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein; pseudokinase ALS2CR2
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
55437
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