IMPDH2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527494
PA5-27494 targets IMPDH2 in WB applications and shows reactivity with Human and mouse samples. The PA5-27494 immunogen is recombit fragment corresponding to a region within amino acids 88 and 291 of Human IMPDH2. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5 ft.-monophosphate into xanthine-5 ft.-monophosphate, which is then converted into guanosine-5 ft.-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in maligt transformation.
|Recombit fragment corresponding to a region within amino acids 88 and 291 of Human IMPDH2|
|Antigen affinity chromatography|
|0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7|
|IMPD2, IMPDH-II, IMP (inosine monophosphate) dehydrogenase 2, IMP oxireductase 2, IMPD 2, IMPDH 2, inosine 5′ phosphate dehydrogenase 2, inosine monophosphate dehydrogenase type II, inosine-5′-monophosphate dehydrogenase 2|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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