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Importin 8 Rabbit anti-Human, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA141599

Catalog No. 01-675-216



Description

Description

Importin 8 is a 1037 amino acid nuclear protein with a RAN binding site. It belongs to RAN-binding protein super family and hence shares an N-terminal sequence motif with importin-beta that appears to account for RAN GTP binding. It binds to the nuclear pore complex (NPC) and is well known as a transport carrier that mediates nuclear import of ribosomal proteins with a classical nuclear localization signal. Importin 8 works by binding to the nuclear pore complex and, along with RANGTP and RANBP1, inhibits the GAP stimulation of the RAN GTPase. Along with transportin it also helps in the nuclear import of SRP19.
Specifications

Specifications

Importin 8
Polyclonal
Unconjugated
IPO8
Liquid
IPO8
Synthetic peptide corresponding to residues 850-900 of human Importin-8.
Protein G
RUO
Antibody
Polyclonal
Human, Non-human Primate
Immunocytochemistry, Immunofluorescence, Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
O15397
FLJ26580, RANBP8
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
10526
Documents
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