Importin 8 Rabbit anti-Human, Non-human primate, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA141599
DescriptionImportin 8 is a 1037 amino acid nuclear protein with a RAN binding site. It belongs to RAN-binding protein super family and hence shares an N-terminal sequence motif with importin-beta that appears to account for RAN GTP binding. It binds to the nuclear pore complex (NPC) and is well known as a transport carrier that mediates nuclear import of ribosomal proteins with a classical nuclear localization signal. Importin 8 works by binding to the nuclear pore complex and, along with RANGTP and RANBP1, inhibits the GAP stimulation of the RAN GTPase. Along with transportin it also helps in the nuclear import of SRP19.
|Synthetic peptide corresponding to residues 850-900 of human Importin-8.|
|Human, Non-human Primate|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|PBS with 0.05% BSA and 0.05% sodium azide|
|-20° C, Avoid Freeze/Thaw Cycles|
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