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Influenza A H1N1 Goat anti-Virus, Polyclonal, Invitrogen™

Goat Polyclonal Antibody

Manufacturer:  Invitrogen PA17221

Catalog No. PA17221


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Description

Description

PA1-7221 detects the influenza A virus (H1N1). This antibody does not react with influenza B, RSV, Parainfluenza 1-3 or Adenovirus, but may ract with chicken cellular proteins. PA1-7221 has been successfully used in immunofluorescence, ELISA, western blotting and immunohistochemistry procedures. The PA1-7221 immunogen is influenza A, strain USSR (H1N1). PA1-7221 may be used in place of neat antiserum in almost any appropiate antibody-based technique. It is also suitable for conjugation purposes.

Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States. The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic. Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible Neuraminidase (NA) surface proteins. The Hemagglutinin protein facilitates viral attachment while Neuraminidase is involved in viral release. These proteins also elicit immune responses that prevent infection or independently reduce viral replication. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. The distinct antigenic properties of the new swine influenza virus compared with seasonal influenza A (H1N1) virus suggest that human immunity against new swine influenza virus is limited, although the age distribution of reported cases suggests some degree of protection in older age groups.
Specifications

Specifications

Influenza A H1N1
Polyclonal
Unconjugated
Liquid
Goat
IgG
1 mL
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C
Primary
Virus
ELISA, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
4-5 mg/mL
PBS with 0.1% sodium azide; pH 7.2
Influenza H1N1; H1N1
Influenza A, strain USSR (H1N1).
Purified
RUO
Antibody
Polyclonal
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