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IP6K2 Rabbit anti-Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA1906

Catalog No. PA1906

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Inositol 1,4,5-trisphosphate (IP3) is a second messenger for many growth factors, hormones, and neurotransmitters and, upon binding to the IP3 receptor (IP3R), triggers the release of intracellular, luminal calcium to the cytosol. Several additional cellular forms of inositol phosphates have been discovered. These include some which have been recently discovered and characterized to possess up to seven or eight phosphate groups, including pyrophosphates (PP-IPs: pyrophosphate-inositol phosphates). It has been proposed that high-energy pyrophosphates may participate in protein phosphorylation. Inositol-hexakisphosphate (IP6) kinase, or PiUS (Pi Uptake Stimulator) has ATP synthase activity and transfers a phosphate from PP-IP5 to ADP to form ATP thus suggesting an important physiological role for PP-IP5 and IP6 kinase.

PA1-906 detects inositol-hexakisphosphate kinase (IP6 kinase) from rat tissues.PA1-906 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~50kDa protein representing IP6 kinase from rat brain extract.PA1-906 immunizing peptide corresponds to amino acid residues 216-233 from human IP6 kinase. PA1-906 immunizing peptide (Cat. # PEP-085) is available for use in neutralization and control experiments.
Specifications

Specifications

IP6K2
Polyclonal
Unconjugated
Ip6k2
Liquid
IP6K2
Synthetic Peptide: P(216) C V L D L K M G T R Q H G D D A S(233).
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Rat
Western Blot
1 mg/mL
PBS with 1mg/mL BSA and 0.05% sodium azide
Q9R0U1
IP6 Kinase
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
59268
Documents
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