INPP5B Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523992
DescriptionCellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). INPP5B encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
|PBS with 0.09% sodium azide|
|5PTase, 75 kDa inositol polyphosphate-5-phosphatase, phosphoinositide 5-phosphatase, type II inositol-1,4,5-trisphosphate 5-phosphatase|
|-20° C, Avoid Freeze/Thaw Cycles|
|Flow Cytometry, Immunohistochemistry, Western Blot|
|KLH conjugated synthetic peptide between 950-979 amino acids from the C-terminal region of human INPP5B|
|Antigen affinity chromatography|
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