SHIP1 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA512463
This antibody is predicted to react with mouse and rat based on sequence homology.INPP5D is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and it is a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5 ft. phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall, the protein functions as a negative regulator of myeliod cell proliferation and survival.
|PBS with 0.09% sodium azide|
|Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1; SH2 domain-containing inositol-5′-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SHIP-1; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; p150Ship; hp51CN; INPP5D; SHIP; SHIP1|
|-20° C, Avoid Freeze/Thaw Cycles|
|KLH conjugated synthetic peptide between 770-796 amino acids from the central region of human INPP5D|
|Ammonium sulfate precipitation, Size-exclusion - Dialysis|
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