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Insulin Mouse anti-Bovine, Human, Porcine, Clone: 7F8, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA110517

Catalog No. 01-671-533


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Description

Description

MA1-10517 detects Insulin from human, bovine, and porcine samples. MA1-10517 has been successfully used in ELISA applications. The MA1-10517 immunogen is purified human Insulin.

Insulin is a peptide hormone secreted by beta cells of the pancreatic islets. It regulates carbohydrate, protein and lipid metabolism by enhancing membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides and synthesis of proteins and nucleic acids. Insulin is 51-amino acid polypeptide product produced from a precursor peptide, proinsulin. Proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds and one molecule of C-peptide. Insulin deficiency results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population. Insulin is also present in tumors of b-cell origin such as insulinoma.
Specifications

Specifications

Insulin
Monoclonal
1 mg/mL
PBS with 0.1% sodium azide; pH 7.4
P01317, P01308, P01315
Ins
Mouse
IgG1
200 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
280829, 3630, 397415
ELISA
7F8
Unconjugated
INS
Liquid
INS
Purified human Insulin.
Affinity Chromatography
RUO
Antibody
Monoclonal
Bovine, Human, Porcine
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